摘要 |
A drug delivery balloon is provided comprising a balloon having a surface, and a coating disposed on at least a portion of the balloon surface, the coating including an cytostatic therapeutic agent, an excipient, and a plasticizer. In accordance with the present subject matter, at least 30% of the coating transfers from the balloon surface within two minutes after inflation of the balloon. Alternatively, at least 30% of the coating transfers from the balloon surface within one minute after inflation. The coating results in an effective pharmacokinetic profile of an cytostatic therapeutic agent in a vasculature or target tissue. |
申请人 |
ABBOTT CARDIOVASCULAR SYSTEMS INC.;STANKUS, JOHN, J.;TROLLSAS, MIKAEL;HOSSAINY, SYED;ZHANG, LIANGXUAN;BERGER, ED;PACETTI, STEPHEN, D.;TONER, JOHN, L. |
发明人 |
STANKUS, JOHN, J.;TROLLSAS, MIKAEL;HOSSAINY, SYED;ZHANG, LIANGXUAN;BERGER, ED;PACETTI, STEPHEN, D.;TONER, JOHN, L. |