发明名称 Biomarker for colorectal cancer
摘要 The present invention relates to new methods for predicting the clinical outcome or determining the treatment course in a subject afflicted with colorectal cancer and for monitoring the progression of colorectal cancer in a subject. Moreover, the present invention relates to a method for stratification of therapy regimen of a subject afflicted with soild tumor entities, such as colorectal cancer, for determining its susceptibility to the treatment with an inhibitor of angiogenesis. Further, the present invention relates to kits allowing performance of the above methods. In particular, the present invention is based on the finding that determining the level or amount of angiopoietin-2 protein in a sample of a subject is useful for conducting the above referenced methods.
申请公布号 EP2293071(A1) 申请公布日期 2011.03.09
申请号 EP20090011423 申请日期 2009.09.07
申请人 UNIVERSITAET ZU KOELN 发明人 HACKER, ULRICH;GOEDE, VALENTIN;COUTELLE, OLIVER
分类号 G01N33/68 主分类号 G01N33/68
代理机构 代理人
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