发明名称 |
ANTIBODIES AGAINST A CANCER-ASSOCIATED EPITOPE OF VARIANT HNRNPG AND USES THEREOF |
摘要 |
<p>The present application provides the amino acid and nucleic acid sequences of heavy and light chain complementarity determining regions of a cancer specific antibody directed to an epitope of variant Heterogeneous Ribonucleoprotein G (HnRNPG). In addition, the application provides cancer specific antibodies and immunoconjugates comprising the cancer specific antibody attached to a toxin or label, and methods of uses thereof. The application also relates to diagnostic methods and kits using the cancer specific antibodies disclosed herein. Further, the application provides novel cancer-associated epitopes and antigens of variant HnRNPG, and uses thereof.</p> |
申请公布号 |
EP2215122(A4) |
申请公布日期 |
2011.03.09 |
申请号 |
EP20080841782 |
申请日期 |
2008.10.23 |
申请人 |
VIVENTIA BIOTECH INC. |
发明人 |
CIZEAU, JEANNICK;CHAHAL, FRANCINA, C. |
分类号 |
C07K16/30;A61K39/00;A61K39/395;A61K47/48;C07K14/21;C07K14/705;C07K16/18;C07K16/28;C07K19/00;C12N15/12;C12N15/13;C12N15/62;G01N33/574;G01N33/58 |
主分类号 |
C07K16/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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