HIV vaccination with a DNA encoding a HIV polypeptide and a HIV polypeptide

摘要

The present invention relates to polynucleotides encoding immunogenic HIV polypeptides. Use of the polynucleotides in applications including immunization, generation of packaging cell lines, and production of HIV polypeptides are also described. Polynucleotides encoding antigenic HIV polypeptides are described, as are uses of these polynucleotides and polypeptide products therefrom, including formulations of immunogenic compositions and uses thereof.