| 发明名称 |
NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS |
| 摘要 |
Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided. |
| 申请公布号 |
EP2291080(A1) |
申请公布日期 |
2011.03.09 |
| 申请号 |
EP20090762826 |
申请日期 |
2009.05.14 |
| 申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
ROBERTS, EDWARD;ROSEN, HUGH;BROWN, STEVEN;GUERRERO, MIGUEL A.;PENG, XUEMEI;PODDUTOORI, RAMULU |
| 分类号 |
C07D271/06;A01N43/82;A61K31/41;C07D401/04;C07D413/04;C07D413/14;C07D471/04 |
主分类号 |
C07D271/06 |
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