发明名称 2-substituted 1-(3,4-difluorophenyl)cyclopropane derivatives
摘要 The invention relates to three intermediates provided by processes for the preparation of certain cyclopropyl carboxylic acid esters and other cyclopropyl carboxylic acid derivatives. trans -(1 R ,2 R )-2-(3,4-difluorophenyl)cyclopropanecarbonyl chloride; trans -(1 R ,2 R )-2-(3,4-difluorophenyl)cyclopropanecarbonyl azide; and trans -(1 R ,2 S )-2-(3,4-difluorophenyl)cyclopropanaminium(2 R ) -2-hydroxy-2-phenylethanoate.
申请公布号 EP2292582(A2) 申请公布日期 2011.03.09
申请号 EP20100183120 申请日期 2001.05.31
申请人 ASTRAZENECA AB 发明人 CLARK, ADRIAN;JONES, ELFYN;LARSSON, ULF, G;MINIDIS, ANNA
分类号 C07C211/40;C07B61/00;C07C27/02;C07C57/60;C07C61/40;C07C67/14;C07C67/347;C07C67/56;C07C69/013;C07C69/618;C07C69/74;C07C209/56;C07C247/22;C07D487/04 主分类号 C07C211/40
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