发明名称 |
Small Streptococcus pyogenes antigens and their use |
摘要 |
The present invention relates to a peptide consisting of one antigen of Streptococcus pyogenes ( S. pyogenes ) of SEQ ID NO: 1 or a functional active variant thereof, optionally further consisting of additional amino acid residue(s); a nucleic acid coding for the same; a pharmaceutical composition, especially a vaccine, comprising said peptide or said nucleic acid; an antibody or functional active fragment thereof specifically binding to the antigen; a hybridoma cell line which produces said antibody; a method for producing said antibody; a pharmaceutical composition comprising said antibody; the use of said peptide or said nucleic acid for the manufacture of a medicament for the immunization or treatment of a subject; the use of said antibody or functional fragment thereof for the manufacture of a medicament for the treatment of an infection; a method of diagnosing a S. pyogenes infection; a method for identifying a ligand capable of binding to said peptide; and the use of said peptide for the isolation and/or purification and/or identification of an interaction partner of the peptide.
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申请公布号 |
EP2292645(A2) |
申请公布日期 |
2011.03.09 |
申请号 |
EP20100010868 |
申请日期 |
2007.07.06 |
申请人 |
INTERCELL AG |
发明人 |
MEINKE, ANDREAS;NAGY, ESZTER;VON GABAIN, ALEXANDER;BERGER, MANFRED;TSCHANUN, BEATRICE;SCHUNN, MICHAEL |
分类号 |
C07K14/315 |
主分类号 |
C07K14/315 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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