发明名称 THIAZOLE COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN KINASE
摘要 The present invention provides a compound of formula I: or a pharmaceutically acceptable derivative thereof. These compounds are inhibitors of protein kinases, particularly inhibitors of GSK3, Aurora2, and Syk mammalian protein kinases. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of utilizing those compounds and compositions in the treatement of various protein kinase mediated disorders.
申请公布号 CA2446756(C) 申请公布日期 2011.03.08
申请号 CA20022446756 申请日期 2002.05.23
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 COCHRAN, JOHN;NANTHAKUMAR, SUGANTHINI;HARRINGTON, EDMUND;WANG, JIAN
分类号 C07D417/04;A61K31/427;A61K31/506;A61P3/10;C07D405/06;C07D405/14;C07D417/14;C07D487/10;C07D521/00;C07F7/18;C07F9/6561 主分类号 C07D417/04
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