发明名称 |
Treatment of neurodegenerative diseases using proteasome modulators |
摘要 |
Methods for modulating proteasome activity in a subject is provided. Proteasome activity is modulated by administering a therapeutically effective amount of proteasome modulating pharmacological agent to a subject. In a preferred embodiment, the proteasome modulating pharmacological agent is a protease inhibitor. In another aspect, a screening assay for detecting and identifying proteasome modulating pharmacological agents to modulate proteasome activity in a subject is also provided.
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申请公布号 |
US7902185(B2) |
申请公布日期 |
2011.03.08 |
申请号 |
US20030453912 |
申请日期 |
2003.06.03 |
申请人 |
ALS THERAPY DEVELOPMENT FOUNDATION, INC. |
发明人 |
RAMESH TENNORE M.;SCOTT SEAN |
分类号 |
A01N43/62;A01N43/04;A61K31/00;A61K31/427;A61K31/472;A61K31/4725;A61K31/496;A61K31/513;A61K31/55;A61K31/551;A61K31/635;A61K31/70;A61K38/55;A61P25/16;A61P25/28;A61P31/00;G01N33/68 |
主分类号 |
A01N43/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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