发明名称 |
Markers for prenatal diagnosis and monitoring |
摘要 |
This application provides the use of novel fetal markers for prenatal diagnosis and monitoring of certain pregnancy-related conditions. More specifically, the invention resides in the discovery that certain CpG islands located on fetal chromosome 21 demonstrate a methylation profile that is distinct from that of the corresponding CpG islands located on maternal chromosome 21. This application also provides kits for diagnosing or monitoring of the relevant conditions. |
申请公布号 |
US7901884(B2) |
申请公布日期 |
2011.03.08 |
申请号 |
US20070784499 |
申请日期 |
2007.04.06 |
申请人 |
THE CHINESE UNIVERSITY OF HONG KONG |
发明人 |
LO YUK MING DENNIS;CHIU ROSSA WAI KWUN;CHIM STEPHEN SIU CHUNG;DING CHUNMING;JIN SHENGNAN;LEE TRACY YUEN HAN;LUN FIONA MIU FUN |
分类号 |
C07H21/04;C12Q1/68 |
主分类号 |
C07H21/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|