发明名称 MMP-2 AND/OR MMP-9 INHIBITOR
摘要 The present invention provides a highly safe pharmaceutical preparation effective for diseases caused by MMP-2 and/or MMP-9. The pharmaceutical preparation contains, as an active ingredient, at least one member selected from the group consisting of thiazole derivatives represented by Formula (1): wherein R1 represents a phenyl group that may have 1 to 3 lower alkoxy groups as substituents on the phenyl ring, and R2 represents a pyridyl group that may have 1 to 3 carboxyl groups as substituents on the pyridine ring, and salts thereof. Such thiazole derivatives have MMP-2 and/or MMP-9 inhibitory activity.
申请公布号 US2011054179(A1) 申请公布日期 2011.03.03
申请号 US20090922374 申请日期 2009.03.13
申请人 发明人 MINATOGUCHI SHINYA;OHNO YASUSHI;YABUUCHI YOUICHI;KOTOSAI KOUNORI;NAGAMOTO HISASHI
分类号 C07D417/04 主分类号 C07D417/04
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