发明名称 |
COMPOSITIONS COMPRISING ANTI-ICAM-1 ANTIBODIES |
摘要 |
There is provided a method of preventing a respiratory infection by administering an effective amount of an agent for regulating ICAM-1 expression. Also provided is a composition for the prevention of respiratory infection including an agent which regulates ICAM expression. method of preventing RSV infection by administering an effective amount of an agent that interferes with the binding of RSV to ICAM-1. A method of preventing RSV infection by administering an effective amount of an agent that down regulates the expression of ICAM-1, thereby decreasing RSV binding to ICAM-1 is also provided. There is provided a method of treating RSV infection by administering an effective amount of an agent for down regulating ICAM-1 expression. A method of blocking RSV-ICAM-1 interaction by administering an effective amount of agents for blocking ICAM sites of binding is provided. Also provided is a compound for blocking RSV-ICAM-1 interaction including an agent for blocking ICAM sites of binding.
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申请公布号 |
US2011052601(A1) |
申请公布日期 |
2011.03.03 |
申请号 |
US20090390246 |
申请日期 |
2009.02.20 |
申请人 |
UNIVERSITY OF SOUTH FLORIDA |
发明人 |
MOHAPATRA SHYAM S.;BEHERA ARUNA;MATSUSE HIROTO;KUMAR MUKESH |
分类号 |
A61K39/42;A61K48/00;A61P11/00;A61P31/12;C07H21/02;C12N15/11;C12N15/113 |
主分类号 |
A61K39/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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