发明名称 CARBOXYLIC ACID COMPOUND
摘要 To find a therapeutic agent and/or a preventive agent for diabetes mellitus or the like having excellent activity and safety. A compound represented by the following general formula (I), or a pharmacologically acceptable salt thereof. In the formula, X represents ═C(R5)- or ═N—; Y represents —O— or —NH—; L represents a bond or a substitutable C1-C3 alkylene group; M represents a substitutable C3-C10 cycloalkyl group, a substitutable C6-C10 aryl group, or a substitutable heterocyclic group; R1 represents a C1-C6 alkyl group, a C3-C10 cycloalkyl group, a C1-C6 haloalkyl group, a C2-C6 alkenyl group, a C2-C6 alkynyl group, a C1-C6 aliphatic acyl group, a C1-C6 alkoxy C1-C6 alkyl group, or a C6-C10 aryl group; and R2, R3, R4, and R5 may be the same or different and each represent a hydrogen atom, a halogen atom, a C1-C3 alkyl group, a C1-C3 haloalkyl group, a C1-C3 alkoxy group, or a nitro group. In this connection, the alkyl group moieties of R1 and R2 may be bonded to each other to form a 5- to 6-membered heterocyclic ring containing one oxygen atom.
申请公布号 US2011053974(A1) 申请公布日期 2011.03.03
申请号 US20100893592 申请日期 2010.09.29
申请人 DAIICHI SANKYO COMPANY, LIMITED 发明人 TODA NARIHIRO;YOSHIDA MASAO;TAKANO RIEKO;INOUE MASAHIRO;HONDA TAKESHI;MATSUMOTO KOJI;NAKASHIMA RYUTARO
分类号 A61K31/4355;A61K31/192;A61K31/196;A61K31/343;A61K31/40;A61K31/426;A61K31/44;A61K31/47;A61P3/04;A61P3/08;A61P3/10;A61P5/50;A61P7/02;A61P9/10;A61P9/12;A61P17/00;A61P19/02;A61P35/00;A61P37/08;C07C59/68;C07C205/56;C07C229/40;C07C317/46;C07C317/48;C07D207/327;C07D213/64;C07D213/74;C07D215/233;C07D277/30;C07D307/83;C07D491/048 主分类号 A61K31/4355
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