发明名称 |
METHODS OF USING FLT3-LIGAND IN THE TREATMENT OF CANCER |
摘要 |
Ligands for flt3 receptors capable of transducing self-renewal signals to regulate the growth, proliferation or differentiation of progenitor cells and stem cells are disclosed. The invention is directed to Flt3-ligand as an isolated protein, the DNA encoding the Flt3-ligand, host cells transfected with cDNAs encoding Flt3-ligand, compositions comprising Flt3-ligand and methods of using Flt3-ligand in hematopoietic cell transplantation.
|
申请公布号 |
US2011053863(A1) |
申请公布日期 |
2011.03.03 |
申请号 |
US20090436548 |
申请日期 |
2009.05.06 |
申请人 |
CELLDEX THERAPEUTICS INC. |
发明人 |
LYMAN STEWART D.;BECKMANN M. PATRICIA |
分类号 |
A61K38/00;A01K67/027;A61K38/18;A61K38/19;A61K48/00;A61P35/00;C07K14/475;C12N5/0789;C12N15/85 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|