METHOD FOR PRODUCING L-AMINO ACID BY INCREASE OF CELLULOUS NADPH

摘要

PROBLEM TO BE SOLVED: To improve the yield of amino acids in fermentation by using the metabolism engineering.

SOLUTION: The method for producing L-amino acids comprises culturing altered bacterial cells having increased amounts of NADPH as compared to unaltered bacterial cells whereby L-amino acid yields from the altered bacterial cells are greater than yields from unaltered bacterial cells. There is also provided a gene encoding phosphoglucoisomerase. The altered bacterial cells comprise at least one enzyme selected from a group comprising a glucose-6-phosphate dehydrogenase, lactonase and 6-phosphogluconate dehydrogenase.

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