| 摘要 |
Vaccines comprising the NEAT domain of iron-regulated surface determinant (Isd) proteins IsdA, IsdB, IsdC, and IsdH (HarA) from Staphylococcus aureus, as well as antibodies, antisense nucleic acids and siRNA specific to the NEAT domains of IsdA, IsdB. IsdC or IsdH (HarA) are described Screening assays for identifying agents that inhibit or interfere with the expression level and/or function of IsdA, IsdB, IsdC or IsdH (HarA) NEAT domain arc also described. |
| 申请人 |
THE UNIVERSITY OF WESTERN ONTARIO;HEINRICHS, DAVID, E.;GRIGG, JASON, C.;VERMEIREN, CHRISTIE;MURPHY, MICHAEL, E., P. |
发明人 |
HEINRICHS, DAVID, E.;GRIGG, JASON, C.;VERMEIREN, CHRISTIE;MURPHY, MICHAEL, E., P. |
