发明名称 |
METHOD FOR REDUCING SCARRING DURING WOUND HEALING USING ANTISENSE COMPOUNDS DIRECTED TO CTGF |
摘要 |
This invention provides a method for reducing hypertropic scarring resulting from dermal wound healing in a subject in need which comprises administering to the subject an antisense oligonucleotide which inhibits expression of connective tissue growth factor (CTGF) in an amount effective to inhibit expression of CTGF and thereby reduce hypertrophic scarring.
|
申请公布号 |
US2011054004(A1) |
申请公布日期 |
2011.03.03 |
申请号 |
US20090547481 |
申请日期 |
2009.08.26 |
申请人 |
EXCALIARD PHARMACEUTICALS, INC.;ISIS PHARMACEUTICALS, INC.;NORTHWESTERN UNIVERSITY |
发明人 |
MUSTOE THOMAS A.;DEAN NICHOLAS M.;SISCO MARK;KRYGER ZOL;BENNETT C. FRANK |
分类号 |
A61K31/7088;A61P17/02 |
主分类号 |
A61K31/7088 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|