发明名称 Method For Manufacturing Aryl Carboxamides
摘要 A process for preparing arylcarboxamides of the formula (I) where Ar =a mono- to trisubstituted phenyl, pyridyl or pyrazolyl ring, where the substituents are selected from halogen, Ci-C4-alkyl and C1-C4-haloalkyl; M =thienyl or phenyl, which may bear a halogen substituent; Q =direct bond, cyclopropylene, fused bicycio[2.2.1]heptane or bicyclo[2.2.1]heptene ring; R1 =hydrogen, halogen, C1-C6-alkyl, C1-C4-alkoxy, C1-C4-haloalkoxy, mono- to trisubstituted phenyl, where the substituents are selected from halogen and trifluoromethylthio, or cyclopropyl; by reacting an acid chloride of the formula (II) with an arylamine (III) in a suitable nonaqueous solvent, wherein, in the absence of an auxiliary base, a) the acid chloride (II) is initially charged, b) a pressure of from 0 to 700 mbar is established, c) the arylamine (III) is metered in in an approximately stoichiometric amount and d) the product of value is isolated.
申请公布号 US2011054183(A1) 申请公布日期 2011.03.03
申请号 US20090990892 申请日期 2009.05.06
申请人 BASF SE 发明人 REICHERT WOLFGANG;KORADIN CHRISTOPHER;SMIDT SEBASTIAN PEER;MAYWALD VOLKER;WOLF BERND;RACK MICHAEL;ZIERKE THOMAS;KEIL MICHAEL
分类号 C07D213/82;C07D231/14 主分类号 C07D213/82
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