| 摘要 |
<p>The present invention discloses a method of treating a head and neck cancer or preventing the development of pre-malignant lesions to this cancer, by administering locally to the oral cavity, a sustained release drug delivery system comprising a drug for the treatment of this cancer or for the prevention of said lesions, and at least one polymer, such that said system is attached to a surface in the oral cavity and remains attached thereto for at least 1 hour, accompanied by release of the drug and maintaining an effective therapeutic concentration thereof in the cavity, for at least 1 hour. Further are disclosed a sustained release drug delivery system and a liquid precursor varnish composition to this system.</p> |
| 申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREWUNIVERSITY OF JERUSALEM, LTD;HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENTLTD.;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;FRIEDMAN, MICHAEL;CZERNIMSKI, RAKEFET;GUTKIND, SILVIO;STEINBERG, DORON;GATI, IRITH;NUDELMAN, ZAKHAR |
发明人 |
FRIEDMAN, MICHAEL;CZERNIMSKI, RAKEFET;GUTKIND, SILVIO;STEINBERG, DORON;GATI, IRITH;NUDELMAN, ZAKHAR |
