| 摘要 |
<p>Spherical, polymorphous or other-form chambered implant parts consist of (A) a partial or complete thick or thin shell with partial or mixed smooth, rough or structured surfaces diametrically penetrated by round(-like), optionally uniform pores; and (B) an inner structure consisting of specified cavities interconnected to the shell. Spherical, polymorphous or other-form chambered implant parts consist of (A) a partial or complete thick or thin shell with partial or mixed smooth, rough or structured surfaces diametrically penetrated by round(like), optionally uniform pores; and (B) an inner structure consisting of a cavity or a conglomerate of spherical shell-covered cavities in direct contact via the shell to the outer shell and connecting to included spherical cavities or hollow spheres, such cavities being interconnected via a diametrical pore system in the shell and the outer shells being open to the exterior. Independent claims are also included for (1) composite implants comprising an implant combined with another implant of different porosity with or without a filler and effective agent and with its cavity system partially or completely filled, the combination being such that the latter implant is mechanically arranged along a central axis, a central cylinder being cut or grinded out or produced in the production of the first implant; (2) composite implants consisting of an implant with a mechanically attached implant of a porous or solid, resorbable or non-resorbable material with or without effective agents; and (3) production of implants by: (i) placing shape-forming elements into a mold with a perforated top and bottom while ensuring the material cannot fall out and firmly closing the mold with a strainer basket; (ii) filling the mold with hot wax of melting point 60-90 (especially 80)[deg]C and hardening the wax; (iii) removing the product from the mold and removing the shape-forming elements, e.g. by dissolving out air-filled polystyrene spheres with acetone, leaving the wax body intact; (iv) filling the resulting hollows system with small shape-forming elements, e.g. sugar or polystyrene spheres; (v) filling the remaining space around the shape-forming elements with a fluid, e.g. an agar-agar/calcium phosphate or hydroxyapatite mixture or a hardenable material such as polymethyl methacrylate; and (vi) solidifying the liquid material and dissolving out the shape-forming elements and removing the wax framework either by dissolution or burning off during sintering at 900-1400[deg]C.</p> |
