发明名称 |
Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein |
摘要 |
The present invention relates to fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing ischemic cardiovascular diseases, using one or more of said peptides in an ELISA (Enzyme Linked Immuno Sorbent Assay).
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申请公布号 |
EP2289922(A1) |
申请公布日期 |
2011.03.02 |
申请号 |
EP20100180835 |
申请日期 |
2002.04.05 |
申请人 |
FORSKARPATENT I SYD AB;CEDARS-SINAI MEDICAL CENTER |
发明人 |
NILSSON, JAN;SHAH, PREDIMAN K |
分类号 |
C07K14/775;G01N33/53;A61K;A61K38/00;A61K38/17;A61K39/00;A61K39/385;A61K39/39;A61K39/395;A61P9/10 |
主分类号 |
C07K14/775 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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