发明名称 ACCELERANTS FOR THE MODIFICATION OF NON-NATURAL AMINO ACIDS AND NON-NATURAL AMINO ACID POLYPEPTIDES
摘要 Disclosed herein are accelerants for the formation of oxime-containing compounds from the reaction of a carbonyl-containing compound and a hydroxylamine-containing compound. The oxime-containing compound, the carbonyl-containing compound and the hydroxylamine-containing compound can each be a non-natural amino acid or a non-natural amino acid polypeptide. Also disclosed is the use of such accelerants to form oxime-containing compounds, the resulting oxime-containing compounds, and reaction mixtures containing such accelerants.
申请公布号 EP1954710(B1) 申请公布日期 2011.03.02
申请号 EP20060837144 申请日期 2006.11.08
申请人 AMBRX, INC. 发明人 TIAN, FENG;MIAO, ZHENWEI
分类号 C07C249/08;A61K47/48;C07C249/14;C07C251/54;C07K1/107;C07K14/61 主分类号 C07C249/08
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