发明名称 Recombinant constructs and their use in reducing gene expression
摘要 Recombinant constructs useful for reducing the expression of endogenous mRNA and any substantially similar endogenous mRNA are disclosed. In particular, a recombinant construct comprising, inter alia, a suitable nucleic acid sequence and its reverse complement can be used to alter the expression of any homologous, endogenous RNA (i.e., the target RNA) which is in proximity to this suitable nucleic acid sequence.
申请公布号 US7897383(B2) 申请公布日期 2011.03.01
申请号 US20080256721 申请日期 2008.10.23
申请人 E. I. DU PONT DE NEMOURS AND COMPANY;PIONEER HI-BRED INTERNATIONAL 发明人 KINNEY ANTHONY J.;GLASSMAN KIMBERLY F.;GORDON-KAMM WILLIAM JAMES;LOWE KEITH S.;NICHOLS SCOTT E.;STECCA KEVIN L.
分类号 C07H21/02;C12N15/09;C07H21/04;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/82;C12Q1/02;C12Q1/68 主分类号 C07H21/02
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