发明名称 MALEIMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER
摘要 The present invention relates to pyrroloquinolinyl-pyrrole-2,5-dione compounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrroloquinolinyl-pyrrole-2,5-dione compounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the present invention.
申请公布号 SI1846406(T1) 申请公布日期 2011.02.28
申请号 SI20060030867T 申请日期 2006.02.09
申请人 ARQULE, INC. 发明人 LI CHIANG J;ASHWELL MARK ANTONY;HILL JASON;MOUSSA MAGDI M.;MUNSHI NERU
分类号 A61K31/473;A61K31/551;A61K31/661 主分类号 A61K31/473
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