STRAIN OF BACTERIUM ESCHERICHIA COLI EB387 FOR PROTECTION OF ANIMALS OF CANINE FAMILY AGAINST TOXICOSES INDUCED BY CYTOTONIC TOXINS OF A1B5, TYPE AND BASED ON IT PROBIOTIC MEDICATION

摘要

FIELD: medicine. ^ SUBSTANCE: strain is obtained by insertion into genome of Escherichia coli, isolated from clinically healthy representative of canine family, of genes, determining synthesis of microcin C51, B-subunit of toxin, as well as vaccine version of elt-operon and A-subunit, enhancing immune response. Strain possesses expressed adhesion to mucous membrane of intestine of animals of canine family. Frozen dried culture of Escherichia coli EB387 represents probiotic medication for protection of animals of canine family against toxicoses, induced by cytotonic toxins of A1B5 type. ^ EFFECT: normalisation and stabilisation of qualitative and quantitative composition of gastrointestinal tract microflora in representatives of canine family. ^ 2 cl, 3 ex