| 摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention refers to pharmacology and medicine, and represents a solid and stable oral dispersion of water-soluble Vinca alkaloid derivative, particularly vinorelbine in at least one polyethylene glycol of molecular weight within 1000 and 6000, wherein a mass ratio of water-soluble vinorelbine and more specifically, firstly vinorelbine ditartrate and, secondly polyethylene glycol is within 1.5:1 and 1:10 and, preferentially within 1:3 and 1:6. ^ EFFECT: invention provides higher stability of Vinca alkaloid derivatives, and especially vinorelbine salts, particularly vinorelbine ditartrate. ^ 14 cl, 3 ex, 2 tbl, 2 dwg |
