Compounds for inflammation and immune-related uses

摘要

Disclosed is a compound of formula (I), wherein L is a linker selected from the group of a covalent bond, -NRCH2-, -CH2NR-, -C(O)-, -NR-C(O)-, -C(O)-NR-, OC(O)-, C(O)O-, C(S)-, -NR-C(S)- or -C(S)-NR-, and the other substituents are disclosed within the specification, or a pharmaceutically acceptable salt thereof. Also disclosed is a method of inhibiting immune cell activation, inhibiting cytokine production or modulating an ion channel in a cell in vitro, comprising administering to the cell the said compound. Use of the said compound for the manufacture of a medicament for inhibiting immune cell activation, inhibiting cytokine production or modulating an ion channel in a cell is also disclosed.