RIBOFLAVIN BASED AEROSOL AND USE AS PLACEBO IN TRIALS

摘要

A method for evaluating an aerosolized test compound includes administering a test compound to a first population of individuals, via inhalation of an aerosol; administering a placebo comprising riboflavin 5 '-phosphate to a second population of individuals, via inhalation of an aerosol; and comparing a biological marker for individuals in the two populations. An aerosol comprising riboflavin 5 '-phosphate (also known as flavin mononucleotide) may be used either as a placebo in clinical trials, or therapeutically.