发明名称 IMMUNOPOTENTIATING G, U-CONTAINING OLIGORIBONUCLEOTIDE
摘要 <P>PROBLEM TO BE SOLVED: To provide an immunopotentiating ribonucleic acid and a homologue of this immunopotentiating ribonucleic acid and to provide a method for utilizing this immunopotentiating nucleic acid and the homologue thereof. <P>SOLUTION: The immunopotentiating composition contains such an isolated RNA oligomer of 5-40 nucleotide length as has a base sequence containing at least one guanine (G) and at least one uracil (U), and according to demand, contains a cationic lipid, wherein in one embodiment, the composition is such that the isolated RNA oligomer is a G, U-rich RNA, and in the other embodiment, the composition is such that the base sequence contains 5'-RURGY-3', wherein R represents purine, U represents uracil, G represents guanine and Y represents pyrimidine. <P>COPYRIGHT: (C)2011,JPO&INPIT
申请公布号 JP2011037863(A) 申请公布日期 2011.02.24
申请号 JP20100211454 申请日期 2010.09.21
申请人 COLEY PHARMACEUTICAL GMBH 发明人 LIPFORD GRAYSON B;BAUER STEFAN;WAGNER HERMANN
分类号 A61K31/7105;G01N33/50;A61K9/127;A61K31/205;A61K31/7088;A61K31/7115;A61K31/712;A61K31/7125;A61K31/713;A61K38/00;A61K38/21;A61K39/00;A61K39/002;A61K39/02;A61K39/12;A61K39/35;A61K39/39;A61K39/395;A61K45/00;A61K45/06;A61K47/20;A61K47/24;A61K48/00;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P33/00;A61P35/00;A61P37/04;C07H;C07K14/705;C12N5/078;C12N5/0784;C12N15/09;C12N15/117;C12Q1/02;C12Q1/68;G01N33/15;G01N33/566 主分类号 A61K31/7105
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