| 发明名称 |
TREATMENT OF PARAOXONASE 1 (PON1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO PON1 |
| 摘要 |
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Paraoxonase 1 (PON1), in particular, by targeting natural antisense polynucleotides of Paraoxonase 1 (PON1). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of PON1. |
| 申请公布号 |
WO2010148065(A9) |
申请公布日期 |
2011.02.24 |
| 申请号 |
WO2010US38785 |
申请日期 |
2010.06.16 |
| 申请人 |
CURNA, INC.;COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA |
发明人 |
COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA |
| 分类号 |
C12N15/113;A61K31/713;A61K48/00;C12N15/52 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
