摘要 |
<P>PROBLEM TO BE SOLVED: To provide a substance exhibiting a health function in a human body by using blossoms which are waste materials in the production of apios, and a food raw material based on such the substance. <P>SOLUTION: The extract of apios blossom is prepared and fractionated by a column chromatographic means, and components are separated and purified by using radical scavenging activity and α-glucosidase inhibitory activity as indices. As a result, as a component having a maltase inhibitory effect, AFL60F28-1 is isolated and identified as (E)-3-(3, 4-dihydroxyphenyl)acrylic acid β-D-glucopyranosyl(caffeoyl β-D-glucopyranoside) or 2-O-[3-(3, 4-dihydroxyphenyl)acryloyl]-D-glucopyranose. As a result of administering an active fraction AFL60 containing the component to mice, the elevation inhibitory effect of blood sugar level is observed in normal mice as well as diabetes model mice. <P>COPYRIGHT: (C)2011,JPO&INPIT |