发明名称 BLOOD GLUCOSE LEVEL ELEVATION INHIBITOR AND FOOD MATERIAL FOR PREVENTING DIABETES BY USING APIOS BLOSSOM
摘要 <P>PROBLEM TO BE SOLVED: To provide a substance exhibiting a health function in a human body by using blossoms which are waste materials in the production of apios, and a food raw material based on such the substance. <P>SOLUTION: The extract of apios blossom is prepared and fractionated by a column chromatographic means, and components are separated and purified by using radical scavenging activity and &alpha;-glucosidase inhibitory activity as indices. As a result, as a component having a maltase inhibitory effect, AFL60F28-1 is isolated and identified as (E)-3-(3, 4-dihydroxyphenyl)acrylic acid &beta;-D-glucopyranosyl(caffeoyl &beta;-D-glucopyranoside) or 2-O-[3-(3, 4-dihydroxyphenyl)acryloyl]-D-glucopyranose. As a result of administering an active fraction AFL60 containing the component to mice, the elevation inhibitory effect of blood sugar level is observed in normal mice as well as diabetes model mice. <P>COPYRIGHT: (C)2011,JPO&INPIT
申请公布号 JP2011037800(A) 申请公布日期 2011.02.24
申请号 JP20090189000 申请日期 2009.08.18
申请人 AOMORI UNIV OF HEALTH & WELFARE;KURAISHI CHIIKI SHINKO KOSHA:KK 发明人 IWAI KUNIHISA;KAWAMURA HITOSHI;MATSUE HAJIME;KITAMURA TSUTOMU;KOWATARI AKIRA;KAWAGISHI KEN
分类号 A61K36/48;A23L1/30;A61P3/10;A61P43/00;C12N9/99 主分类号 A61K36/48
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