The present invention relates to immunoconjugates. In particular embodiments, the present invention relates to immunoconjugates comprising at least one single-chain effector moiety and two or more antigen binding moieties. In addition, the present invention relates to nucleic acid molecules encoding such immunoconjugates, vectors and host cells comprising such nucleic acid molecules. The invention further relates to methods for producing the immunoconjugates of the invention, and to methods of using these immunoconjugates in the treatment of disease.
申请公布号
WO2011020783(A2)
申请公布日期
2011.02.24
申请号
WO2010EP61810
申请日期
2010.08.13
申请人
ROCHE GLYCART AG;HOSSE, RALF;MOESSNER, EKKEHARD;SILACCI-MELKKO, MICHELA;UMANA, PABLO
发明人
HOSSE, RALF;MOESSNER, EKKEHARD;SILACCI-MELKKO, MICHELA;UMANA, PABLO