| 摘要 |
This invention relates to the use of short nucleic acid molecules that modulate RhoA kinase (RhoA) expression. The invention includes compounds, compositions and methods useful for silencing the expression and activity of the RhoA gene involved in the RhoA kinase pathway. In one embodiment, the present invention provides short nucleic acid molecules, such as siRNA, which can be used in treating, preventing, or inhibiting symptoms associated with acute spinal cord injuries. |
| 申请人 |
RELIANCE LIFE SCIENCES PVT. LTD.;MURALI, KRISHNA, ADEPALLI;KRITI, BIMALENDU, RAY;BHARAT, KUMAR;SHAILAJA, CHILE;BHARAT, SAINI;VIKRAM, RAJAGOPAL;KUMAR, MANOJ, A., S.;VENKATA, RAMANA |
发明人 |
MURALI, KRISHNA, ADEPALLI;KRITI, BIMALENDU, RAY;BHARAT, KUMAR;SHAILAJA, CHILE;BHARAT, SAINI;VIKRAM, RAJAGOPAL;KUMAR, MANOJ, A., S.;VENKATA, RAMANA |
