METHODS AND COMPOSITIONS FOR THE DETECTION OF CANCER
摘要
Various embodiments of this invention relate generally to targeted activation and delivery of therapeutic drugs to cells that produce prostate specific antigen (PSA), prostate specific membrane antigen (PSMA) or human glandular kallikrein (hK2). Various further embodiments relate more specifically to PSMA-specific peptide prodrugs that become activated to yield therapeutic drugs. Further aspects of various embodiments of the present invention also relate to methods and compositions for treating or preventing cancers and methods and compositions for detecting and/or imaging cancers.
申请公布号
WO2010107909(A3)
申请公布日期
2011.02.24
申请号
WO2010US27657
申请日期
2010.03.17
申请人
THE JOHNS HOPKINS UNIVERSITY;DENMEADE, SAMUEL RAY;ISAACS, JOHN THOMAS;CHRISTENSEN, SOEREN BROGGER
发明人
DENMEADE, SAMUEL RAY;ISAACS, JOHN THOMAS;CHRISTENSEN, SOEREN BROGGER