发明名称 Enhanced purification of antibody fragments by apatite chromotography
摘要 Methods are disclosed for use of apatite chromatography, particularly without reliance upon phosphate gradients, for purification or separation of at least one intact non-aggregated antibody, or at least one immunoreactive antibody fragment, from an impure preparation. Integration of such methods into multi-step procedures with other fractionation methods are additionally disclosed.
申请公布号 EP2287174(A1) 申请公布日期 2011.02.23
申请号 EP20100178856 申请日期 2009.01.16
申请人 BIO-RAD LABORATORIES, INC. 发明人 GAGNON, PETER S.
分类号 C07K1/16;C12N15/10 主分类号 C07K1/16
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