发明名称 2,4-Di(phenylamino)-pyrimidines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders
摘要 <p>Novel pyrimidine derivatives of formula (I) and their use for the manufacture of a medicament for the treatment or prevention of a disease which responds to inhibition of FAK and/or ALK and/or ZAP-70 and/or IGF-IR. in which: n' is selected from 1,2 and 3; R' 1 is selected from phenyl, pyridinyl, pyrazolyl and pyrimidinyl; and R' 2 and R' 3 are as described herein.</p>
申请公布号 EP2287156(A1) 申请公布日期 2011.02.23
申请号 EP20100010291 申请日期 2004.08.13
申请人 NOVARTIS AG;IRM LLC 发明人 GARCIA-ECHEVERRIA, CARLOS;KANAZAWA, TAKANORI;KAWAHARA, EIJI;MASUYA, KEIICHI;MATSUURA, NAOKO;MIYAKE, TAKAHIRO;OHMORI, OSAMU;UMEMURA, ICHIRO;STEENSMA, RUO;CHOPIUK, GREG;JIANG, JIQING;WAN, YONGQIN;DING, QIANG;ZHANG, QIONG;GRAY, NATHANAEL, SCHIANDER;KARANEWSKY, DONALD
分类号 C07D239/48;A61K31/506;A61K35/00;A61P29/00;A61P37/00;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D405/14;C07D498/04 主分类号 C07D239/48
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