发明名称 |
Humanized antibodies that sequester amyloid beta peptide |
摘要 |
A method to treat conditions characterized by formation of amyloid plaques both prophylactically and therapeutically is described. The method employs humanized antibodies which sequester soluble A&bgr; peptide from human biological fluids or which preferably specifically bind an epitope contained within position 13-28 of the amyloid beta peptide A&bgr;. |
申请公布号 |
US7892545(B2) |
申请公布日期 |
2011.02.22 |
申请号 |
US20080028641 |
申请日期 |
2008.02.08 |
申请人 |
ELI LILLY AND COMPANY;WASHINGTON UNIVERSITY |
发明人 |
HOLTZMAN DAVID M;DEMATTOS RONALD;BALES KELLY R.;PAUL STEVEN M.;TSURUSHITA NAOYA;VASQUEZ MAXIMILIANO |
分类号 |
A61K39/395;C12N15/09;A61K;A61K39/00;A61P;A61P25/28;C07K;C07K16/18;C12N;C12N5/10;C12N15/13;C12R1/91 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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