USE OF INDOLE DERIVATIVES AS NURR-1 ACTIVATORS FOR TREATING PARKINSON’S DISEASE.

摘要

The present invention relates to an indole-derived compound, particularly useful in therapy, and characterized in that the compound is selected from among iii) the compounds of formula (I), where: R1 is a halogen atom or a trifluoromethyl group; R2 is a hydrogen atom or a (C1-C4)alkyl group; R3 is an isopropyl (1-methylethyl) group or a te/t/σ-butyl (1,1-dimethylethyl), and n = 3 or 4. The invention further relates to the pharmaceutically acceptable salts of said compounds of formula (I). The invention can be used in the treatment of neurodegenerative diseases and particularly of Parkinson’s disease.