发明名称 Method of screening for gamma-secretase activity
摘要 The present invention relates to an improved process for determining γ-secretase activity and for detecting γ-secretase, a subunit protein of γ-secretase, or a γ-secretase-like proteinase. In particular, the present invention relates to processes for the identification of a γ-secretase or of a cDNA which codes for a γ-secretase, a subunit protein of γ-secretase, or a γ-secretase-like proteinase. Another embodiment of the present invention relates to processes for the identification of substances which can inhibit the activity of γ-secretase, or a γ-secretase-like proteinase.
申请公布号 US7892778(B2) 申请公布日期 2011.02.22
申请号 US20040849423 申请日期 2004.05.19
申请人 SANOFI-AVENTIS DEUTSCHLAND GMBH 发明人 HOPPE EDMUND;PERAUS GISELA;ROTHBLATT JONATHAN;LEBERER EKKEHARD;MERCKEN LUC;DREISLER SYLVIE
分类号 C12Q1/37;C12N15/62 主分类号 C12Q1/37
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