发明名称 Post-translational modifications and Clostridial neurotoxins
摘要 The present invention discloses modified neurotoxins with altered biological persistence. In one embodiment, the modified neurotoxins are derived from Clostridial botulinum toxins. Such modified neurotoxins may be employed in treating various conditions, including but not limited to muscular disorders, hyperhidrosis, and pain.
申请公布号 US7893202(B1) 申请公布日期 2011.02.22
申请号 US20070624111 申请日期 2007.01.17
申请人 ALLERGAN, INC. 发明人 STEWARD LANCE E.;FERNANDEZ-SALAS ESTER;SPANOYANNIS ATHENA;AOKI K. ROGER;LIN WEI-JEN
分类号 A61K39/00;A61K38/00;C07K1/00;C12N9/52 主分类号 A61K39/00
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