发明名称 |
Method of identifying a MHC class I restricted T cell response |
摘要 |
Described are peptides and polypeptides derived from the MUC-1 polypeptide which are able to activate Cytotoxic T Lymphocyte (CTL) response, analogues of such peptides and polypeptides nucleotide sequences encoding such peptides and polypeptides and therapeutic uses thereof. Moreover, indications for selecting appropriate minimal antigenic MUC-1 polypeptides with reference to the HLA-type of the patient to be treated or tested are described.
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申请公布号 |
US7892828(B2) |
申请公布日期 |
2011.02.22 |
申请号 |
US20090578499 |
申请日期 |
2009.10.13 |
申请人 |
TRANSGENE S.A.;IMPERIAL CANCER RESEARCH TECHNOLOGY. LDT. |
发明人 |
TAYLOR-PAPADIMITRIOU JOYCE;HEUKAMP LUKAS CARL;OFFRINGA RIENK;MELIEF CORNELIS JOHANNA MARIA;ACRES BRUCE;THOMAS MIREILLE |
分类号 |
C12N15/09;A61K31/7088;A61K35/12;A61K35/76;A61K38/00;A61K38/17;A61K39/00;A61K39/39;A61K48/00;A61P35/00;A61P37/06;A61P43/00;C07K7/06;C07K14/47;C12N1/15;C12N1/19;C12N1/21;C12N5/00;C12N5/02;C12N5/10;C12N15/12;C12Q1/02;G01N33/50;G01N33/53;G01N33/68 |
主分类号 |
C12N15/09 |
代理机构 |
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