METHOD OF FLUORESCENT DIAGNOSTICS IN COURSE OF PHOTODYNAMIC THERAPY OF EYE DISEASES

摘要

FIELD: medicine. ^ SUBSTANCE: invention relates to medicine, ophthalmology and can be used for fluorescent diagnostics in the course of photodynamic therapy of eye diseases. Photosensitiser (PS) is introduced to patient intravenously, fluorescent diagnostics is carried out by means of device which contains a source of laser irradiation, system of its delivery with optic adaptor for transpuppilar irradiation, homogenising element, microscope, highly sensitive black-and white videocamera with filter for formation of image of examined part of eye, system of videoinformation presentation. Used filter has the following characteristics: optic density of range 400-750 nm - not less that 4; for range 780-890 nm - not more than 1. System of videoinformation presentation is represented by personal computer with software for image registration and processing. In the course of diagnostics patient's eye is irradiated by wide homogeneous laser beam with 6-12 mm diametre with wavelength corresponding to maximum of light irradiation absorption by chlorine PS. Power density is 20-40 mW/ cm2. ^ EFFECT: method ensures clearness of PS fluorescence visualization in the course of photodynamic therapy with simultaneous visualisation of irradiated details of eye structure in light spot with 6-12 mm diametre. ^ 5 dwg