发明名称 METHOD OF DETERMINING FUNCTIONAL CELL DEATH
摘要 FIELD: medicine. ^ SUBSTANCE: spectrum of combinational light dispersion from one examined cell is measured by means of optic confocal coherent tomography, using probing radiation with wavelength which does not get into band of cell chromophore absorption, cell is irradiated by resonance laser radiation, which gets into band of cell chromophore absorption and causes hyperthermia. Intensity of laser radiation is increased to value, which causes change of spectral components of combinational dispersion. Functional cell death is determined by threshold level of laser impact at which irreversible changes of spectral components of combinational impact arise. ^ EFFECT: application of method allows to realise non-invasive control of functional cell death in case of hyperthermia and determine threshold of functional cell injury irrespective of radiation type by irreversible change of molecular spectra of combinational cell dispersion. ^ 5 cl, 6 dwg 1 ex
申请公布号 RU2412442(C1) 申请公布日期 2011.02.20
申请号 RU20090131570 申请日期 2009.08.20
申请人 GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "SARATOVSKIJ GOSUDARSTVENNYJ UNIVERSITET IM. N.G. CHERNYSHEVSKOGO" 发明人 AKCHURIN GARIF GAZIZOVICH;AKCHURIN GEORGIJ GARIFOVICH;BRATASHOV DANIIL NIKOLAEVICH;GORIN DMITRIJ ALEKSANDROVICH;PORTNOV SERGEJ ALEKSEEVICH
分类号 G01N33/49 主分类号 G01N33/49
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