发明名称 TRICYCLIC ANTIBIOTICS
摘要 The invention relates to antibacterial compounds of formula (I) wherein U represents CH or N; W represents CH or N; R1 represents alkoxy, halogen or CN; ring A represents a pyrrolidin-1,3-diyl-, a piperidin-1,3-diyl or a morpholin-2,4-diyl group and B represents CH2; or ring A is selected from the groups drawn below: wherein R2 represents H, F or hydroxymethyl, and B is absent; G represents a group selected from the group consisting of —CH═CH-E, wherein Y1, Y2, Y3 and Z independently represent CH or N; Q represents O or S; and E represents phenyl which is mono- or di-substituted wherein the substituents are each independently halogen; and to pharmaceutically acceptable salts of such compounds.
申请公布号 US2011039836(A1) 申请公布日期 2011.02.17
申请号 US20090988205 申请日期 2009.04.14
申请人 ACTELION PHARMACEUTICALS LTD. 发明人 HUBSCHWERLEN CHRISTIAN;RUEEDI GEORG;SURIVET JOHN-PHILIPPE;ZUMBRUNN-ACKLIN CORNELIA
分类号 A61K31/5415;A61K31/4355;A61K31/436;A61K31/5025;A61K31/5383;A61P31/04;C07D487/04;C07D491/04;C07D491/14;C07D498/04;C07D513/04 主分类号 A61K31/5415
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