| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a method able to perform long term NSAID (non-steroidal anti-inflammatory drug) treatment. <P>SOLUTION: The use of a pharmaceutical composition containing cobiprostone or a pharmaceutically acceptable salt, ester, ether or amide thereof together with an NSAID in the long term treatment of a disease or condition which is one of indications for NSAID use in a human patient is provided. In the use, cobiprostone is administered at least 36 mcg/day to the patient who is taking the NSAID. The patient can take the NSAID for a long period of time by administering cobiprostone or the pharmaceutically acceptable salt, ester, ether or amide thereof in combination with the NSAID. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |
