| 发明名称 |
METHOD FOR MAKING 3A-HYDROXY, 3B- SUBSTITUTED-5A-PREGNAN-20-ONES |
| 摘要 |
Applicants have discovered a method for the stereoselective and regioselective synthesis of 3α-hydroxy, 3&bgr;-methyl-5α-pregnan-20-one (ganaxolone) comprising reacting 5α-pregnane-3,20-dione; with an organometallic methylating agent in an inert solvent to provide a compound of the formula
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| 申请公布号 |
US2011040112(A1) |
申请公布日期 |
2011.02.17 |
| 申请号 |
US20100854226 |
申请日期 |
2010.08.11 |
| 申请人 |
MARINUS PHARMACEUTICALS, INC. |
发明人 |
SHAW KENNETH;HUTCHISON ALAN |
| 分类号 |
C07J7/00 |
主分类号 |
C07J7/00 |
| 代理机构 |
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代理人 |
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