发明名称 BENZIMIDAZOLE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS
摘要 The invention relates to compounds of formula (I) wherein R1 represents aryl, which is unsubstituted, or mono-, di-, or tri-substituted wherein the substituents are independently selected from the group consisting of (C1-4)alkyl, (C1-4)alkoxy, halogen, and trifluoromethyl; R2 represents hydrogen, or —CO—R21; R21 represents (C1-5)alkyl, (C1-3)fluoroalkyl, or (C3-6)cycloalkyl; m represents the integer 2, or 3; p represents the integer 2 or 3; and R3 represents hydrogen, or (C1-5)alkyl; and pharmaceutically acceptable salts of such compounds. These compounds are useful as calcium channel blockers.
申请公布号 US2011039905(A1) 申请公布日期 2011.02.17
申请号 US20090989443 申请日期 2009.04.23
申请人 HUBLER FRANCIS;HILPERT KURT;RENNEBERG DORTE 发明人 HUBLER FRANCIS;HILPERT KURT;RENNEBERG DORTE
分类号 A61K31/4184;A61P9/00;C07D235/14 主分类号 A61K31/4184
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