发明名称 CYCLIC INDOLE-3-CARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS
摘要 The present invention relates to cyclic indole-3-carboxamides of the formula I, wherein A, R, R10, R20, R30, R40, n, p and q have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. Specifically, they inhibit the enzyme renin and modulate the activity of the renin-angiotensin system, and are useful for the treatment of diseases such as hypertension, for example. The invention furthermore relates to processes for the preparation of the compounds of the formula I, their use and pharmaceutical compositions comprising them.
申请公布号 US2011039830(A1) 申请公布日期 2011.02.17
申请号 US20100845317 申请日期 2010.07.28
申请人 SANOFI-AVENTIS 发明人 STEINHAGEN HENNING;SCHEIPER BODO;MATTER HANS;STILZ HANS ULRICH;MCCORT GARY
分类号 A61K31/551;A61K31/454;A61K31/4545;A61P9/00;A61P13/12;A61P27/06;C07D401/14;C07D403/06 主分类号 A61K31/551
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