| 发明名称 |
ANTIBODY- ENDOSTATIN FUSION PROTEIN AND ITS VARIANTS |
| 摘要 |
Chimeric molecules comprising endostatin and all or a portion of a tumor antigen specific binding molecule for use in treating tumors. The chimeric molecule, includes endostatin, endostatin mutants and variants and an antibody or aptamer specific for a desired tumor antigen. Methods of treating cancer comprise administering the chimeric fusion molecules.
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| 申请公布号 |
US2011038865(A1) |
申请公布日期 |
2011.02.17 |
| 申请号 |
US20080665007 |
申请日期 |
2008.06.26 |
| 申请人 |
UNIVERSITY OF MIAMI |
发明人 |
SHIN SEUNG-UON;ROSENBLATT JOSEPH DAVID;MORRISON SHERIE L. |
| 分类号 |
A61K39/395;A61P35/00;C07H21/04;C07K19/00;C12N5/10 |
主分类号 |
A61K39/395 |
| 代理机构 |
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