发明名称 Novel Compounds
摘要 The invention relates to at least one compound of general formula I wherein R1 is phenyl, pyridinyl, thienyl, furanyl, imidazolyl, pyrrolyl, triazolyl, thiazolyl, or pyridine N-oxide, where each R1 phenyl and R1 heteroaromatic ring may optionally and independently be substituted by 1, 2 or 3 substituents selected from CF3, methyl, iodo, bromo, fluoro, and chloro; R2 is independently selected from ethyl and isopropyl; R3 is hydrogen or fluoro; R4 is —NH2 or —NHSO2R5; and R5 is hydrogen, —CF3, or C1-C6 alkyl, or pharmaceutically acceptable salts thereof; at least one process for making at least one compound in accordance with Formula I; at least one method for treating at least one δ receptor associated condition with at least one compound in accordance with Formula I; and at least one pharmaceutical composition comprising at least one compound in accordance with Formula I.
申请公布号 US2011039858(A1) 申请公布日期 2011.02.17
申请号 US20100911167 申请日期 2010.10.25
申请人 ASTRAZENECA AB 发明人 BROWN WILLIAM;WALPOLE CHRISTOPHER;PLOBECK NIKLAS
分类号 A61K31/497;C07D295/14;A61K31/495;A61K31/496;A61P1/04;A61P25/00;A61P25/04;A61P25/22;A61P29/00;C07D233/24;C07D233/64;C07D233/94;C07D295/155;C07D307/52;C07D307/66;C07D333/20 主分类号 A61K31/497
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